Combining different line crosses for mapping quantitative trait loci using the identical by descent-based variance component method
C Xie, DDG Gessler, S Xu - Genetics, 1998 - academic.oup.com
Mapping quantitative trait loci (QTLs) is usually conducted with a single line cross. The
power of such QTL mapping depends highly on the two parental lines. If the two lines are
fixed for the same allele at a putative QTL, the QTL is undetectable. On the other hand, if a
QTL is segregating in the line cross and is detected, the estimated variance of the QTL
cannot be extrapolated beyond the statistical inference space of the two parental lines. To
reduce the likelihood of missing a QTL and to increase the statistical inference space of the …
power of such QTL mapping depends highly on the two parental lines. If the two lines are
fixed for the same allele at a putative QTL, the QTL is undetectable. On the other hand, if a
QTL is segregating in the line cross and is detected, the estimated variance of the QTL
cannot be extrapolated beyond the statistical inference space of the two parental lines. To
reduce the likelihood of missing a QTL and to increase the statistical inference space of the …
Combining different line crosses for mapping quantitative trait loci using the identical by descent-based variance component method.
XCQ Xie ChongQing, DDG Gessler, XSZ Xu ShiZhong - 1998 - cabidigitallibrary.org
Mapping quantitative trait loci (QTLs) is usually conducted with a single line cross. The
power of such QTL mapping depends highly on the two parental lines. If the two lines are
fixed for the same allele at a putative QTL, the QTL is undetectable. On the other hand, if a
QTL is segregating in the line cross and is detected, the estimated variance of the QTL
cannot be extrapolated beyond the statistical inference space of the two parental lines. To
reduce the likelihood of missing a QTL and to increase the statistical inference space of the …
power of such QTL mapping depends highly on the two parental lines. If the two lines are
fixed for the same allele at a putative QTL, the QTL is undetectable. On the other hand, if a
QTL is segregating in the line cross and is detected, the estimated variance of the QTL
cannot be extrapolated beyond the statistical inference space of the two parental lines. To
reduce the likelihood of missing a QTL and to increase the statistical inference space of the …
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