To compare the visual performance after implantation of three aberration-correcting aspherical intraocular lens (IOL).

Seventy-seven eyes of 77 cataract patients were divided into three groups: 26 eyes implanted with a non-constant aberration IOL (LUCIA 601P IOL, Zeiss Company, Germany); 26 eyes implanted with a spherical aberration −0.18μm IOL (CT ASPHINA 509M, Zeiss Company, Germany) and 27 eyes implanted with a spherical aberration −0.27μm IOL (AMO Tecnis ZCB00, Johnson & Johnson Surgical Vision, USA). Three months after operation, the distance visual acuity, wavefront aberrometry, contrast sensitivity, intraocular stray light, IOL decentration, and tilt were evaluated.

Three months postoperatively, no statistically significant differences were found in uncorrected distance visual acuity and corrected distance visual acuity (p≥.83). The RMS for total ocular coma was statistically significantly lower in the Lucia group (p=.03) and spherical aberration was statistically significantly lower in the Tecnis group (p<.01). No statistically significant differences were observed among the three lenses in higher order aberration (p=.85) and in contrast sensitivity under both photopic and mesopic lighting conditions (p≥.05). The intraocular stray light was statistically significantly better in the Lucia group (p=.04). No statistically significant differences were observed with respect to IOL decentration (p=.75) and tilt (p=.89).

Cataract surgery with non-constant aberration IOL resulted in lower coma and better intraocular stray light than with the spherical aberration −0.18μm and −0.27μm IOLs despite equivalent postoperative levels of visual acuity and contrast sensitivity.