Correlation of visual acuity and central macular thickness in diabetic macular edema
A El Matri Hassairi, A Chebil… - Acta …, 2015 - Wiley Online Library
A El Matri Hassairi, A Chebil, M Ben Abdallah, R Maamouri, N Chaker, L El Matri
Acta Ophthalmologica, 2015•Wiley Online LibraryPurpose To investigate the correlation of retinal thickness measured with SD OCT and visual
acuity in eyes with diabetic macular edema (DME) before and after intravitreal injection of
anti‐VEGF Methods Seventy‐four patients (96 eyes) with DME who underwent three
monthly intravitreal injection of bevacizumab (IVB) as their first treatment. Type of DM,
duration, treatment, laboratory examinations, history of cardiovascular disease,
hypertension, hyperlipidemia, diabetic nephropathy, were documented. Logarithm of the …
acuity in eyes with diabetic macular edema (DME) before and after intravitreal injection of
anti‐VEGF Methods Seventy‐four patients (96 eyes) with DME who underwent three
monthly intravitreal injection of bevacizumab (IVB) as their first treatment. Type of DM,
duration, treatment, laboratory examinations, history of cardiovascular disease,
hypertension, hyperlipidemia, diabetic nephropathy, were documented. Logarithm of the …
Purpose
To investigate the correlation of retinal thickness measured with SD OCT and visual acuity in eyes with diabetic macular edema (DME) before and after intravitreal injection of anti‐VEGF
Methods
Seventy‐four patients (96 eyes) with DME who underwent three monthly intravitreal injection of bevacizumab (IVB) as their first treatment. Type of DM, duration, treatment, laboratory examinations, history of cardiovascular disease, hypertension, hyperlipidemia, diabetic nephropathy, were documented. Logarithm of the minimum angle of resolution (logMAR) best corrected visual acuity (BCVA) was evaluated using the international vision test chart. Foveal thickness was measured by SD OCT.
Results
The correlation coefficients for visual acuity (VA) versus OCT center point thickness were 0.57 at baseline and 0.47, 0.38, and 0.40 at 1, 3, and 6 months post‐laser photocoagulation. A subset of eyes showed paradoxical improvements in VA with increased center point thickening (5–13% at the three time points) or paradoxical worsening of VA with a decrease in center point thickening (12–24% at the three time points).
Conclusions
There is modest correlation between OCT‐measured center point thickness and VA, and modest correlation of changes in retinal thickening and visual acuity following focal laser treatment for DME. In addition, paradoxical changes in VA and retinal thickening may be observed. Indeed, retinal thickness only accounts for up to 27% of variability in concurrently measured VA suggesting that other factors are important determinants of VA in the presence of diabetic macular edema.
Wiley Online Library以上显示的是最相近的搜索结果。 查看全部搜索结果