Cortical spreading depression (CSD), a slowly propagated wave of depolarization followed
by suppression of brain activity, is a remarkably complex event that involves dramatic …

Cortical spreading depression (CSD) is associated with a dramatic failure of brain ion
homeostasis as well as efflux of excitatory amino acids from nerve cells and increased energy …

… migraine … cortical spreading depression in migraine pathophysiology. Imaging studies in
migraineurs demonstrated hemodynamic changes consistent with cortical spreading depression …

… the term spreading depression (SD) to describe a transient “depression” of electrocorticographic
activity that lasts up to several minutes and slowly “spreads” in all directions in cortex by …

… Inhibition of cortical spreading depression after chronic treatment with migraine prophylactic
… Measurements were made on the first cortical spreading depression in each experiment. …

… For several decades, it has been generally assumed that migraine’s pathophysiology is
based on a phenomenon called Cortical Spreading Depression (CSD), which is thought to be a …

… 3 mm/min across the primary visual cortex. Leão described cortical spreading depression
(CSD) in rabbits in 1944 and noticed its similarity to the migraine aura. Despite these scattered …

… Spreading depression (SD) is a slowly propagating wave of neuronal and glial … cortex or
other brain areas after electrical, mechanical or chemical depolarizing stimulations. Cortical SD (…

… ing findings indicate that the migraine aura is due to cortical spreading depression (CSD), a
… vated threshold for cortical spreading depression in mice with muta45 min measuring period…

… depression. Here, we review recent anatomical data on the trigeminovascular pathway and
… by cortical spreading depression, a novel understanding of the neural substrate of migraine-…