The relevance of dyadic coping (DC), a concept how couples cope with stressors together, has been established in different contexts (eg, daily hassles, mental and physical health) and is related to different outcomes such as relationship satisfaction, relationship quality and stability, psychological well-being, and child behavior. The current systematic review aims at providing an integration of the field of research on couple’s DC with child-related stressors which are understood as demands that arise for couples due to becoming or being parents. DC and related search terms were used for the literature search in PsycINFO, Psyndex, and Medline. We included 55 publications (reporting empirical data on 6,779 couples in total) including quantitative, qualitative, and mixed-methods studies published between 1990 and 2020. We applied a narrative synthesis approach organizing the results around six identified areas of child-related stressors: pregnancy and transition to parenthood, parenting, child mental health, child disability, child chronic physical illness, and child death. Overall, results show the importance of DC for both individual and relationship functioning in the context of child-related stress. Surprisingly, effects of parental DC on child outcomes remained understudied, although the existing studies yield promising results for child adjustment. In conclusion, adapting a “we”-perspective, mutual understanding and support is of importance not only to overcome the stressor but also to grow together as a couple. As DC plays a significant role for couples to cope in a resilient way when facing child-related stressors it should be more promoted in couple-and family counseling and therapy.(PsycInfo Database Record (c) 2022 APA, all rights reserved)