[HTML][HTML] Cytotoxic profile of natural and some modified bufadienolides from toad Rhinella schneideri parotoid gland secretion
GA Cunha-Filho, IS Resck, BC Cavalcanti, CÓ Pessoa… - Toxicon, 2010 - Elsevier
Cutaneous secretions of toad species are an important source of bufadienolides,
compounds that exhibit interesting structural features and biopharmacological properties.
Here we describe the isolation of bufadienolides from the Brazilian toad Rhinella schneideri
parotoid glands secretion, including: marinobufagin (1), bufalin (2), telocinobufagin (3),
hellebrigenin (4), and the atypical 20S, 21R-epoxymarinobufagin (5) besides the
widespread β-sitosterol (6). Starting from natural bufadienolides four derivatives were …
compounds that exhibit interesting structural features and biopharmacological properties.
Here we describe the isolation of bufadienolides from the Brazilian toad Rhinella schneideri
parotoid glands secretion, including: marinobufagin (1), bufalin (2), telocinobufagin (3),
hellebrigenin (4), and the atypical 20S, 21R-epoxymarinobufagin (5) besides the
widespread β-sitosterol (6). Starting from natural bufadienolides four derivatives were …
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