… in sepsis. In this review, we focus on DAMPs, NETs, and explore their interplay during sepsis
… therapeutic interventions targeting both DAMPs and NETs in experimental sepsis (Table 1). …

… of immune cell death is the DAMPs release and NETs formation, both of which … sepsis,
strongly indicating that DAMPs and NETs are critical in the development of severe sepsis…

… traps (NETs), their components acting as DAMPs, and DAMPs triggering NET formation
during … Additionally, mitochondrial DNA can be released, as well, for instance during sepsis or …

… TLR4 recognizes the interaction between PRRs and DAMPs due to the inflammatory
reactions induced by different pathogens and elicited by different types of injury. Cytokines …

… the pathogenesis of sepsis as DAMPs.31 The significance of such DAMPs and their usefulness
… Aside from this, in the LPS-induced sepsis model, when nucleosomes and HMGB1 were …

… In this review, we discuss several sepsis-induced DAMPs and … DAMPs as biomarkers and
therapeutic targets for sepsis. … -edged sword functions of DAMPs for the treatment of sepsis. …

… NET promotes inflammation. In the extracellular space, host cell-free DNA can serve as a
damage-associated molecular pattern (DAMP). … are also considered DAMPs since they activate …

… ] and its function in inflammation and sepsis. In acute lung diseases, … Sepsis or ARDS
triggers HMGB1, thus strongly activating the innate immunity. However, HMGB1 also induces NET …

… and progression of sepsis and its potential therapeutic role in sepsis, … of sepsis and with new
strategies for the treatment of sepsis. … for sepsis is anti-NETosis and neutralization of DAMPs …

… (DAMPs). We aimed to review the molecular mechanisms of the early phases of sepsis,
focusing on PAMPs, DAMPs, … /DAMPs, we analyzed their role in the different organs affected by …