… (DAMPs; released and/expressed by damaged/killed host cells). Upon recognition of MAMPs
and DAMPs… lead to severe systemic inflammatory condition called sepsis in response to the …

… NET formation is dependent on PAMPs (lipopolysaccharide [LPS]) and DAMPs (HMGB1)
which can activate neutrophils leading to the release of NETs. We found that patients with ALD …

… with sepsis and discuss the novel roles of DAMPs on neutrophil … These DAMPs have been
shown to increase in sepsis … Moreover, inhibition of DAMPs in experimental sepsis has been …

… in NETs participate in ED as DAMPs, … NETs-induced ED to treat sepsis, many researchers
have devoted themselves to finding NETs-related drugs to alleviate the development of sepsis. …

… Citation15,Citation16 Therefore, given the dual roles of NETs in sepsis, clarifying how NETs
… possibility that macrophages and NETs were jointly involved in sepsis-induced lung injury. …

… (DAMP) molecule, participates in multiple processes of various inflammatory diseases through
binding to its corresponding receptors. In the early phase, sepsis is … of sepsis. Therefore, …

… As DAMPs, NETs also induce damage and inflammatory responses in several pathological
scenarios in different organs by opposing the NETosis of neutrophils 50 . Among the …

… (DAMPs) released along with NETosis or from necrotic neutrophils also contribute to the
pathogenesis of sepsis. … influence the coagulation disorder during sepsis. Moreover, extensive …

… understanding of the clinical ‘sepsis syndrome’ limited our … to our studies of mitochondrial
DAMP release in trauma [9]. … the immediate release of sterile DAMPs from wound sites that …

… sepsis-like” responses in other, particularly traumatic, attacks (48) . Accordingly, mitochondrial
DAMPs … histones released within NETs are recognized by the host as DAMPs and thereby …