… in the presence of NET, which may be relevant in the context of sepsis and DIC. A part of
this mechanism can be explained by the extracellular delivery of TF by NETs favoring FVIIa-…

… DAMPs, such as histones from NETs, exacerbate tubular epithelial cell injury and elicit …
We previously reported increased NET production in CLP-induced sepsis mice, whereas …

… , we introduce the pathology of DAMPs and NETs, and their … DAMPs and NETs, the new
approach targeting DAMPs and … involvement of NETs in the pathogenesis of sepsis, connective …

… Indeed, circulating levels of many DAMPs are associated with severity and … sepsis and
trauma-induced organ injury in patients (2). The ability of some DAMPs to generate sepsis-like …

… , there exist the neutrophil recognition of flagellin, exotoxins, other PAMPs and DAMPs by …
for the detection of other PAMPs and DAMPs as well as the cytoplasmic low potassium …

… During the course of sepsis-associated cell death, DAMPs (such as DNA, histones and
HMGB1) are released from host cells and act as proinflammatory mediators (33-35). Thus, we …

… findings in this study reinforce the proof-of-principle that “hitting back” against the toxic
effects of NETs holds promise as a new approach to sepsis. … DAMPs and NETs in sepsis …

… This study was the first to demonstrate that EP alleviated NET formation and sepsis-induced …
DAMPs induce neutrophil extracellular traps, resulting in intestinal cell injury or death. Ethyl …

… patterns (DAMP) include both PAMP and alarmins. Inflammation is the primary response
to DAMP. … DAMP being inflammation inducers (Table 2) are recognized by pattern-recognition …

… , and the prevailing view is that during sepsis, the LPS emitted by bacteria activates … box-1
(HMGB1), a prototypic DAMP, is involved in NET-mediated neuronal damage in the ischaemic …