Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction caused
by a dysregulated or over-reactive host response to infection. During sepsis… with sepsis. …

… to have an emerging role in sepsis by perpetuating inflammatory signals and … of sepsis,
DAMPs can be released by death cells but also actively by activated cells. PAMPs and DAMPs …

Background Neutrophil extracellular traps (NETs) are involved in the development of sepsis-induced
acute respiratory distress syndrome (ARDS). Glycyrrhizin (GL), the main active …

… , NET-associated mtDNA release can act as a damaged associated molecular pattern (DAMP) …
from sepsis subjects with ARDS, indicate that NETs play a dual role in ALI associated with …

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response
to infection. 1 These dysregulated host responses underpin the clinical phenotypes that …

… mucosal barrier of the host, it can cause sepsis depending on its load and virulence. The …
progression to sepsis, due to the release of endogenous molecules by injured cells (DAMPs or …

… Extracellular CIRP is a damage-associated molecular pattern (DAMP) in sepsis and leading
to organ injury and increased mortality rates 4 . Elevated plasma levels of CIRP were later …

… of necrotizing infections and sepsis because of inadequate … In murine models of sepsis,
knockout of essential neutrophil … system since injury (DAMPS) causes downregulation of many …

… of NET formation in abdominal sepsis is still scarce. Thus, to understand the signaling
mechanism of NET formation and it’s role in abdominal sepsis, we … We detected NETs by electron …

… Coagulation in sepsis, immunothrombosis. PAMPs and DAMPs trigger TF expression on
monocytes and NET release by neutrophils. NETs create places for platelet binding and …