SOLUBILITY ENHANCEMENT OF ANTICANCER (METHOTREXATE) BY USING PAMAM DENDRIMER AS A SOLUBILIZING AGENT

NK Verma, PK Tripathi, U Srivastava… - … -NATURAL VOLATILES & …, 2021 - nveo.org
… by which PAMAM dendrimers apply their solubilizing effect. The insufficiency of studies
investigating the effect of temperature on dendrimer-mediated solubility enhancement is yet …

A comparative study on solubility improvement of tetracycline and dexamethasone by poly (propylene imine) and polyamidoamine dendrimers: An insight into …

F Najafi, M Salami‐Kalajahi… - … Research Part A, 2020 - Wiley Online Library
… 2005) examined the solubility enhancement of nicotinic acid … types of dendrimers including
PAMAM and PPI dendrimers is … dendrimers have been used to improve the solubility of …

Dendrimers: a new race of pharmaceutical nanocarriers

P Mittal, A Saharan, R Verma… - BioMed Research …, 2021 - Wiley Online Library
Dendrimer solubility also … dendrimer complexes were evaluated for solubility, stability, and
in vitro release studies. The PEGylated polymers showed maximum solubility enhancement

Polyamidoamine dendrimer-polyethylene glycol hydrogel for solubility enhancement and sustained release of diflunisal

Z Kegley, M Makay, J Rogers, K Phelps… - Journal of Sol-Gel …, 2022 - Springer
… a reported solubility of … dendrimers are used to enhance the solubility of diflunisal as well
as to be an active ingredient for in situ hydrogel formation. Experiments show that the solubility

Dendimer-Mediated Solubilization, Formulation Development and in Vitroin Vivo Assessment of Piroxicam

RN Prajapati, RK Tekade, U Gupta… - Molecular …, 2009 - ACS Publications
dendrimer at pH 7.4 referred to as 0.2-D 3 P 7.4 (3.0G) and 0.2-D 4 P 7.4 (4.0G) resulted in
significant enhancements of PXM solubility … G dendrimer-mediated solubility enhancement. …

Pharmaceutical and biomedical potential of PEGylated dendrimers

V Gajbhiye, P Vijayaraj Kumar… - Current …, 2007 - ingentaconnect.com
… have generated interest in solubility enhancement of poorly soluble hydrophobic drugs. …
groups assist in dendrimer mediated solubility enhancement. Dendrimer based solubility en…

[PDF][PDF] Enhanced solubility of non-steroidal anti-inflammatory drugs by hydroxyl terminated S-triazine based dendrimers

RM Patel, HN Patel, D Gajjar, PM Patel - Asian J Pharm Clin Res, 2014 - Citeseer
DendrimersDendrimer-mediated solubility enhancement of drugs has been reportedand
depends on factors such as generation size and terminal functionality [12].Dendrimers have …

Polyethylene glycol–polyamidoamine dendritic micelle as solubility enhancer and the effect of the length of polyethylene glycol arms on the solubility of pyrene in …

H Yang, JJ Morris, ST Lopina - Journal of colloid and interface science, 2004 - Elsevier
… By increasing the dendrimer concentration, a slow increase of pyrene solubility … of dendrimer
concentrations, we found pyrene solubility enhancement increased as micelle or dendrimer

Polyamidoamine dendrimer hydrogel for enhanced delivery of antiglaucoma drugs

CA Holden, P Tyagi, A Thakur, R Kadam… - … , biology and medicine, 2012 - Elsevier
… PAMAM dendrimers are able to increase the water solubility … the water solubility enhancement
properties of dendrimers, … the PEG layer.21, 22 As dendrimers have been integrated into a …

[PDF][PDF] Dendrimer-a novel scaffold for drug delivery

T Garg, O Singh, S Arora, R Murthy - Int J Pharm Sci Rev Res, 2011 - researchgate.net
… It has been estimated that approximately 40 ibuprofen molecules interact with G4
PAMAM dendrimer at pH 10.5 causing a considerable enhancement of drug solubility36. …