Development of oral CTL vaccine using a CTP-integrated Sabin 1 poliovirus-based vector system
SS Han, J Lee, Y Jung, MH Kang, JH Hong, MS Cha… - Vaccine, 2015 - Elsevier
We developed a CTL vaccine vector by modification of the RPS-Vax system, a mucosal
vaccine vector derived from a poliovirus Sabin 1 strain, and generated an oral CTL vaccine
against HIV-1. A DNA fragment encoding a cytoplasmic transduction peptide (CTP) was
integrated into the RPS-Vax system to generate RPS-CTP, a CTL vaccine vector. An HIV-1
p24 cDNA fragment was introduced into the RPS-CTP vector system and a recombinant
poliovirus (rec-PV) named vRPS-CTP/p24 was produced. vRPS-CTP/p24 was genetically …
vaccine vector derived from a poliovirus Sabin 1 strain, and generated an oral CTL vaccine
against HIV-1. A DNA fragment encoding a cytoplasmic transduction peptide (CTP) was
integrated into the RPS-Vax system to generate RPS-CTP, a CTL vaccine vector. An HIV-1
p24 cDNA fragment was introduced into the RPS-CTP vector system and a recombinant
poliovirus (rec-PV) named vRPS-CTP/p24 was produced. vRPS-CTP/p24 was genetically …
Development of oral CTL vaccine using a CTP-integrated Sabin 1 poliovirus-based vector system.
HSS Han SeungSoo, LJ Lee Jinjoo, JYD Jung YiDeul… - 2015 - cabidigitallibrary.org
We developed a CTL vaccine vector by modification of the RPS-Vax system, a mucosal
vaccine vector derived from a poliovirus Sabin 1 strain, and generated an oral CTL vaccine
against HIV-1. A DNA fragment encoding a cytoplasmic transduction peptide (CTP) was
integrated into the RPS-Vax system to generate RPS-CTP, a CTL vaccine vector. An HIV-1
p24 cDNA fragment was introduced into the RPS-CTP vector system and a recombinant
poliovirus (rec-PV) named vRPS-CTP/p24 was produced. vRPS-CTP/p24 was genetically …
vaccine vector derived from a poliovirus Sabin 1 strain, and generated an oral CTL vaccine
against HIV-1. A DNA fragment encoding a cytoplasmic transduction peptide (CTP) was
integrated into the RPS-Vax system to generate RPS-CTP, a CTL vaccine vector. An HIV-1
p24 cDNA fragment was introduced into the RPS-CTP vector system and a recombinant
poliovirus (rec-PV) named vRPS-CTP/p24 was produced. vRPS-CTP/p24 was genetically …
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