[HTML][HTML] Developmental pharmacology—drug disposition, action, and therapy in infants and children

GL Kearns, SM Abdel-Rahman… - … England Journal of …, 2003 - Mass Medical Soc
GL Kearns, SM Abdel-Rahman, SW Alander, DL Blowey, JS Leeder, RE Kauffman
New England Journal of Medicine, 2003Mass Medical Soc
For those using drugs to treat infants and children, the integration of developmental
pharmacology is crucial to appropriate clinical practice. Changes in metabolic capacity,
distribution sites, and organ function all affect the way in which medications are handled in
the very young. This review examines the developmental changes that profoundly affect the
responses of children to medications and related therapies.
For those using drugs to treat infants and children, the integration of developmental pharmacology is crucial to appropriate clinical practice. Changes in metabolic capacity, distribution sites, and organ function all affect the way in which medications are handled in the very young. This review examines the developmental changes that profoundly affect the responses of children to medications and related therapies.
The New England Journal Of Medicine
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