Differences in absorption, distribution, metabolism and excretion of xenobiotics between the paediatric and adult populations
M Strolin Benedetti, R Whomsley… - … on drug metabolism & …, 2005 - Taylor & Francis
… for differences in drug absorption and disposition during development. Therefore, due to
different absorption, distribution, metabolism or excretion of a given drug at different ages, the …
different absorption, distribution, metabolism or excretion of a given drug at different ages, the …
Disposition of xenobiotics: species differences
K Rozman - Toxicologic Pathology, 1988 - journals.sagepub.com
… testinal absorption of xenobiotics was thought to be similar between species. … as differences
in excretion itself, may be responsible for species differences in the elimination of xenobiotics…
in excretion itself, may be responsible for species differences in the elimination of xenobiotics…
Intestinal absorption and metabolism of xenobiotics
RS Chhabra - Environmental health perspectives, 1979 - ehp.niehs.nih.gov
… Mice showed no difference between absorption of biliary excreted 203Pb and of 203Pb
administered into duodenum in rats without cannulation of the bile duct. Presence of bile …
administered into duodenum in rats without cannulation of the bile duct. Presence of bile …
Absorption and distribution of xenobiotics.
FG Standaert - Environmental Health Perspectives, 1988 - ehp.niehs.nih.gov
… body is the difference between the amount absorbed and the … This relationship between rate
of metabolism and enzyme … of the xenobiotic is sufficient to saturate the elimination enzymes…
of metabolism and enzyme … of the xenobiotic is sufficient to saturate the elimination enzymes…
Metabolism of xenobiotics of human environments
E Croom - Progress in molecular biology and translational …, 2012 - Elsevier
… of xenobiotic-metabolizing enzymes may be quite different in … , xenobiotics and their metabolites
are also excreted from the … route of elimination for chemicals that are well absorbed and …
are also excreted from the … route of elimination for chemicals that are well absorbed and …
Xenobiotic absorption, distribution, metabolism, and excretion
MR Franklin - Principles of Toxicology: environmental and …, 2014 - books.google.com
… II conjugation of xenobiotics, including variations present in the … xenobiotics and their
metabolites are eliminated from the … of xenobiotic pharmacokinetics—absorption, distribution, …
metabolites are eliminated from the … of xenobiotic pharmacokinetics—absorption, distribution, …
[PDF][PDF] Metabolism and toxicokinetics of xenobiotics
MB Abou-Donia, EM Elmasry… - Handbook of …, 2002 - ndl.ethernet.edu.et
… affects their distribution, metabolism, and elimination. … drug metabolism by a mechanism
that is different from the other … similar rates of uptake and clearance of a xenobiotic. Chemicals …
that is different from the other … similar rates of uptake and clearance of a xenobiotic. Chemicals …
[PDF][PDF] Inter-species variations in the metabolism of xenobiotics
RT Williams - 1974 - researchgate.net
… absorption, distribution, excretion and the rate and pattern of … species, (3) a comparison of
man and his near neighbours … far away is the rat from man in the metabolism of xenobiotics. …
man and his near neighbours … far away is the rat from man in the metabolism of xenobiotics. …
Cutaneous metabolism of xenobiotics
J Kao, MP Carver - Drug metabolism reviews, 1990 - Taylor & Francis
… on skin metabolism as it pertains to dermal absorption, in … to distinguish cutaneous from
systemic metabolic processes, … the systemic distribution and elimination are estimated from …
systemic metabolic processes, … the systemic distribution and elimination are estimated from …
Sex-dependent metabolism of xenobiotics
CA Mugford, GL Kedderis - Drug metabolism reviews, 1998 - Taylor & Francis
… differences in xenobiotic metabolism exist in … metabolism and elimination of xenobiotics,
the levels and composition of isoforms of renal cytochromes P450 may be very important from a …
the levels and composition of isoforms of renal cytochromes P450 may be very important from a …