Direct oral anticoagulants in extremely obese patients: OK to use?

S Moll, DJ Crona, K Martin - Research and practice in thrombosis …, 2019 - rpthjournal.org
Extreme obesity—also referred to as severe, grade III, or morbid obesity—is defined as a
body mass index (BMI)> 40 kg/m2, and occurs in 7.7% of the adult US population. 1 This
translates to nearly 20 million extremely obese adults living in the US. 2 Considering the
prevalence of atrial fibrillation (AF), there may be at least 615 000 extremely obese adults
with atrial fibrillation in the US. 3 As 67%-88% of AF patients are on anticoagulation, 4 this
suggests that at least 500 000 extremely obese individuals in the US with AF have an …
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