The lung is highly exposed to the external environment. For this reason, the lung needs to
handle a number of potential threats present in inhaled air such as viruses or bacteria.
Dendritic cells (DCs) and macrophages (MFs) play an important role in orchestrating the
immune responses to these challenges. The severe lung inflammation caused by some
pathogens poses a unique challenge to the immune system: the potential insult must be
eliminated rapidly whereas tissue inflammation must be controlled in order to avoid …