Does registration of PET and planning CT images decrease interobserver and intraobserver variation in delineating tumor volumes for non–small-cell lung cancer?

JL Fox, R Rengan, W O'Meara, E Yorke, Y Erdi… - International Journal of …, 2005 - Elsevier
Purpose: To compare tumor volume delineation using registered positron emission
tomography (PET)/CT vs. side-by-side image sets. Methods and Materials: A total of 19
patients with non-small-cell lung cancer had 18-fluorine-deoxyglucose (FDG)-PET scans
registered with planning CT scans. The disease was Stage I-II in 26%, IIIA in 42%, and IIIB in
32%. Two radiation oncologists contoured 9 tumor volumes using registered images
(registered) and 10 using separate FDG-PET images as a guide (nonregistered). A third …
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