Dopamine D2 receptor binding in the human brain is associated with the response to painful stimulation and pain modulatory capacity
N Hagelberg, IK Martikainen, H Mansikka, S Hinkka… - Pain, 2002 - Elsevier
The pain modulatory role of dopamine D2 receptors of the human forebrain was studied by
determining the association between dopamine D2 receptor binding potential and the
response to experimental pain. Nineteen healthy male volunteers participated in a
dopamine D2 receptor positron emission tomography study. The extrastriatal regions of
interest studied with [11C] FLB 457 as radioligand (n= 11) were the anterior cingulum, the
medial and lateral thalamus, the medial and lateral frontal cortex, and the medial and lateral …
determining the association between dopamine D2 receptor binding potential and the
response to experimental pain. Nineteen healthy male volunteers participated in a
dopamine D2 receptor positron emission tomography study. The extrastriatal regions of
interest studied with [11C] FLB 457 as radioligand (n= 11) were the anterior cingulum, the
medial and lateral thalamus, the medial and lateral frontal cortex, and the medial and lateral …
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