Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats

PM Johnson, PJ Kenny - Nature neuroscience, 2010 - nature.com
… Whatever the underlying mechanisms, our findings demonstrate that addiction-like
compulsive responding for palatable food can emerge in obese rats, and indicate that deficits in …

[HTML][HTML] Addiction-like reward dysfunction and compulsive eating in obese rats: Role for dopamine D2 receptors

PM Johnson, PJ Kenny - Nature neuroscience, 2010 - ncbi.nlm.nih.gov
… Whatever the underlying mechanisms, our findings demonstrate that addiction-like
compulsive responding for palatable food can emerge in obese rats, and suggest that deficits in …

Role of striatal dopamine signaling in compulsive eating associated with obesity

RM O'Connor, PJ Kenny - Current Opinion in Behavioral Sciences, 2016 - Elsevier
… Similar addiction-like food seeking behaviors that are resistant to punishment have also …
to earn food by overweight rats also coincides with marked deficits in brain reward function, …

Corrigendum: Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats.

PM Johnson, PJ Kenny - 2010 - psycnet.apa.org
… from casual to compulsive drug-taking. Accordingly, we detected compulsive-like feeding
behavior in obese but not lean rats, measured as palatable food consumption that was …

Reward sensitivity deficits in a rat model of compulsive eating behavior

CF Moore, MZ Leonard, NM Micovic… - …, 2020 - nature.com
… of obesity and binge eating have observed downregulated DA signaling, lower DA turnover,
and reduced activity of the dopamine … these dual components in an addiction-like disorder. …

Dopamine D2 receptors and striatopallidal transmission in addiction and obesity

PJ Kenny, G Voren, PM Johnson - Current opinion in neurobiology, 2013 - Elsevier
… to the emergence compulsive eating or drug use in obesity and … We provided rats with
almost unlimited daily access to a ‘… This paper established that addiction-like responding for …

[HTML][HTML] Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats (2010)

PM Johnson, PJ Kenny - yourbrainonporn.com
… Whatever the underlying mechanisms, our findings demonstrate that addiction-like
compulsive responding for palatable food can emerge in obese rats, and indicate that deficits in …

Linking the Features of Food Addiction and Drug Addiction: A New Narrative of Dopamine D2 Receptors and Beyond

PG Brasiel, SCPD Luquetti - … of Substance Misuse and Addictions: From …, 2022 - Springer
… , obesity with compulsive eating behaviors involves reward circuitry … the reward system,
promotes addiction-like eating, and … in obese rats: role for dopamine D2 receptors. Nat Neurosci …

Animal models of compulsive eating behavior

M Di Segni, E Patrono, L Patella, S Puglisi-Allegra… - Nutrients, 2014 - mdpi.com
… in humans, addiction-like behaviors in rats can be found only … to down-regulate dopaminergic
reward circuitry through the … substance use disorder, obesity, and compulsive behavior [89,…

Striatocortical pathway dysfunction in addiction and obesity: differences and similarities

D Tomasi, ND Volkow - Critical reviews in biochemistry and …, 2013 - Taylor & Francis
… over rewarding behaviors (such as binge eating disorder and … striatal dopamine (DA)
signaling (decreased D2 receptors) in … Compulsive-like feeding behavior in obese rats has been …