[HTML][HTML] Durvalumab after chemoradiotherapy in stage III nonsmall-cell lung cancer

SJ Antonia, A Villegas, D Daniel… - … England Journal of …, 2017 - Mass Medical Soc
… may up-regulate PD-L1 expression in tumor cells, 20-22 which is a predictive … to durvalumab,
we hypothesized that durvalumab would provide clinical benefit after chemoradiotherapy. …

[HTML][HTML] Five-year survival outcomes from the PACIFIC trial: durvalumab after chemoradiotherapy in stage III nonsmall-cell lung cancer

DR Spigel, C Faivre-Finn, JE Gray… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
durvalumab after chemoradiotherapy. An estimated 42.9% of patients randomly assigned
to durvalumab … 33.1% of patients randomly assigned to durvalumab remain alive and free of …

Real world data of durvalumab consolidation after chemoradiotherapy in stage III non-small-cell lung cancer

HA Jung, JM Noh, JM Sun, SH Lee, JS Ahn, MJ Ahn… - Lung Cancer, 2020 - Elsevier
… PFS after CCRT treatment in patients with stage III non-squamous cell lung cancer was 8.9–…
with unresectable stage III non-small cell lung cancer: Hoosier Cancer Research Network), …

[HTML][HTML] Durvalumab after chemoradiotherapy in stage III non-small cell lung cancer

P Tomasini, L Greillier, A Boyer, A Jeanson… - Journal of thoracic …, 2018 - ncbi.nlm.nih.gov
Durvalumab after chemoradiotherapy in stage III non-small cell lung cancer … Regarding
consolidation treatment of unresectable stage III NSCLC after chemo-radiotherapy, a phase III

Patient-reported outcomes with durvalumab after chemoradiotherapy in stage III, unresectable non-small-cell lung cancer (PACIFIC): a randomised, controlled, phase …

R Hui, M Özgüroğlu, A Villegas, D Daniel… - The Lancet …, 2019 - thelancet.com
… , stage III non-small-cell lung cancer is poor. Although use of durvalumab after concurrent
chemoradiotherapy … and to show that durvalumab does not result in worse PROs than placebo. …

[HTML][HTML] Durvalumab showed long and durable effects after chemoradiotherapy in stage III non-small cell lung cancer: results of the PACIFIC study

T Uemura, T Hida - Journal of thoracic disease, 2018 - ncbi.nlm.nih.gov
… therapy were durable but those with placebo were not. If consolidation treatment with
durvalumab after chemoradiotherapy improves OS, even in resectable stage IIIA patients, the …

Durvalumab After Chemoradiotherapy in Patients With Unresectable Stage III NonSmall Cell Lung Cancer

MJ Mooradian, L Cai, A Wang, Y Qiao… - JAMA Network …, 2024 - jamanetwork.com
… Two patients discontinued durvalumab after completing 26 infusions and restarted …
durvalumab after CRT as the standard of care for patients with unresectable stage III NSCLC. …

[HTML][HTML] Four-year survival with durvalumab after chemoradiotherapy in stage III NSCLC—an update from the PACIFIC trial

C Faivre-Finn, D Vicente, T Kurata, D Planchard… - Journal of Thoracic …, 2021 - Elsevier
… durable PFS and sustained OS benefit with durvalumab after chemoradiotherapy. An
estimated 49.6% of patients randomized to durvalumab remain alive at 4 years (placebo, 36.3%), …

[HTML][HTML] Overall survival with durvalumab after chemoradiotherapy in stage III NSCLC

SJ Antonia, A Villegas, D Daniel… - … England Journal of …, 2018 - Mass Medical Soc
… help restore systemic and long-term immune response after chemoradiotherapy. … durvalumab
in patients with stage III, unresectable NSCLC who did not have disease progression after

[HTML][HTML] Durvalumab therapy following chemoradiation compared with a historical cohort treated with chemoradiation alone in patients with stage III nonsmall cell …

A Desilets, F Blanc-Durand, S Lau, T Hakozaki… - … Journal of Cancer, 2021 - Elsevier
… -world study of durvalumab use after chemoradiation in stage III nonsmall cell lung cancer.
… use of the PD-L1 inhibitor durvalumab after concurrent CRT in patients with unresectable …