Effect of high-frequency (10-kHz) spinal cord stimulation in patients with painful diabetic neuropathy: a randomized clinical trial
EA Petersen, TG Stauss, JA Scowcroft… - JAMA …, 2021 - jamanetwork.com
Importance Many patients with diabetic peripheral neuropathy experience chronic pain and
inadequate relief despite best available medical treatments. Objective To determine whether
10-kHz spinal cord stimulation (SCS) improves outcomes for patients with refractory painful
diabetic neuropathy (PDN). Design, Setting, and Participants The prospective, multicenter,
open-label SENZA-PDN randomized clinical trial compared conventional medical
management (CMM) with 10-kHz SCS plus CMM. Participants with PDN for 1 year or more …
inadequate relief despite best available medical treatments. Objective To determine whether
10-kHz spinal cord stimulation (SCS) improves outcomes for patients with refractory painful
diabetic neuropathy (PDN). Design, Setting, and Participants The prospective, multicenter,
open-label SENZA-PDN randomized clinical trial compared conventional medical
management (CMM) with 10-kHz SCS plus CMM. Participants with PDN for 1 year or more …
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