Effects of interferon-α, verapamil and dacarbazine in the treatment of advanced malignant melanoma
R Andersson, PÅ Hofer, K Riklund-Åhlström… - Melanoma …, 2003 - journals.lww.com
Abstract Treatment of patients with metastatic melanoma with either dacarbazine (DTIC) or
interferon-α (IFNα) as single drugs, or in combination, results in a response rate of
approximately 15–20%. This study evaluated the activity and toxicity following treatment with
a combination of DTIC, IFNα2b and verapamil (VPL). Thirty patients with disseminated
metastatic melanoma received DTIC 250 mg/m 2 on days 1–5 of a 4 week schedule, IFNα2b
3 MIU on days 1–5 each week, and VPL 80 mg three times a day throughout the cycle, until …
interferon-α (IFNα) as single drugs, or in combination, results in a response rate of
approximately 15–20%. This study evaluated the activity and toxicity following treatment with
a combination of DTIC, IFNα2b and verapamil (VPL). Thirty patients with disseminated
metastatic melanoma received DTIC 250 mg/m 2 on days 1–5 of a 4 week schedule, IFNα2b
3 MIU on days 1–5 each week, and VPL 80 mg three times a day throughout the cycle, until …
以上显示的是最相近的搜索结果。 查看全部搜索结果