Efficacy of self-guided internet-based cognitive behavioral therapy in the treatment of depressive symptoms: a meta-analysis of individual participant data

E Karyotaki, H Riper, J Twisk, A Hoogendoorn… - JAMA …, 2017 - jamanetwork.com
Importance Self-guided internet-based cognitive behavioral therapy (iCBT) has the potential
to increase access and availability of evidence-based therapy and reduce the cost of
depression treatment. Objectives To estimate the effect of self-guided iCBT in treating adults
with depressive symptoms compared with controls and evaluate the moderating effects of
treatment outcome and response. Data Sources A total of 13 384 abstracts were retrieved
through a systematic literature search in PubMed, Embase, PsycINFO, and Cochrane …
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