Efficient co-transduction of adenoviral vectors encoding carcinoembryonic antigen and survivin into dendritic cells by the CAR-TAT adaptor molecule enhance anti …
HS Kim, CH Kim, MY Park, JS Park, HM Park, HJ Sohn… - Immunology letters, 2010 - Elsevier
Because multiple tumor antigens, including carcinoembryonic antigen (CEA) and survivin
(SVV), have been frequently observed in human colorectal cancer, we investigated whether
the expression of both CEA and SVV by co-transduction of adenovirus vectors into dendritic
cells (DCs) could improve anti-tumor immunity in a murine colorectal cancer model. The
adaptor fusion protein of Coxsackie and adenovirus receptor and TAT-protein transduction
domain (CAR-TAT) enhanced co-transduction of adenovirus vectors encoding CEA …
(SVV), have been frequently observed in human colorectal cancer, we investigated whether
the expression of both CEA and SVV by co-transduction of adenovirus vectors into dendritic
cells (DCs) could improve anti-tumor immunity in a murine colorectal cancer model. The
adaptor fusion protein of Coxsackie and adenovirus receptor and TAT-protein transduction
domain (CAR-TAT) enhanced co-transduction of adenovirus vectors encoding CEA …
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