[HTML][HTML] Eimeria tenella: specific EtAMA1-binding peptides inhibit sporozoite entry into host cells
D Ma, Y Huang, C Ma, L Zhang, J Wang, D Wang, J Li… - Poultry Science, 2019 - Elsevier
Avian coccidiosis caused by Eimeria inflicts high economic losses to the poultry industry.
Application of drugs and live vaccines presents particular challenges in pathogen resistance
and cost, hence alternative anti-coccidial strategies are needed. In this study, peptides that
specifically bind E. tenella AMA1 (EtAMA1) were screened from a phage display peptide
library. The positive clones of target phages were characterized by ELISA after four rounds
of biopanning. The binding capabilities with EtAMA1 and sporozoite proteins for the two …
Application of drugs and live vaccines presents particular challenges in pathogen resistance
and cost, hence alternative anti-coccidial strategies are needed. In this study, peptides that
specifically bind E. tenella AMA1 (EtAMA1) were screened from a phage display peptide
library. The positive clones of target phages were characterized by ELISA after four rounds
of biopanning. The binding capabilities with EtAMA1 and sporozoite proteins for the two …
Eimeria tenella: specific EtAMA1-binding peptides inhibit sporozoite entry into host cells.
MDX Ma DeXing, HYC Huang YuChen… - 2019 - cabidigitallibrary.org
Avian coccidiosis caused by Eimeria inflicts high economic losses to the poultry industry.
Application of drugs and live vaccines presents particular challenges in pathogen resistance
and cost, hence alternative anti-coccidial strategies are needed. In this study, peptides that
specifically bind E. tenella AMA1 (EtAMA1) were screened from a phage display peptide
library. The positive clones of target phages were characterized by ELISA after four rounds
of biopanning. The binding capabilities with EtAMA1 and sporozoite proteins for the two …
Application of drugs and live vaccines presents particular challenges in pathogen resistance
and cost, hence alternative anti-coccidial strategies are needed. In this study, peptides that
specifically bind E. tenella AMA1 (EtAMA1) were screened from a phage display peptide
library. The positive clones of target phages were characterized by ELISA after four rounds
of biopanning. The binding capabilities with EtAMA1 and sporozoite proteins for the two …
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