Focal adhesion kinase (FAK) is a cytoplasmic nonreceptor tyrosine kinase that enables
activation by growth factor receptors or integrins in various types of human cancers. The
kinase‐dependent and kinase‐independent scaffolding functions of FAK modulate the
authentic signaling and fundamental functions not only in cancer cells but also in tumor
microenvironment to facilitate cancer progression and metastasis. The overexpression and
activation of FAK are usually investigated in primary or metastatic cancers and correlated …

Focal adhesion kinase (FAK) is a cytoplasmic nonreceptor tyrosine kinase that enables
activation by growth factor receptors or integrins in various types of human cancers. The
kinase-dependent and kinase-independent scaffolding functions of FAK modulate the
authentic signaling and fundamental functions not only in cancer cells but also in tumor
microenvironment to facilitate cancer progression and metastasis. The overexpression and
activation of FAK are usually investigated in primary or metastatic cancers and correlated …