… the aged heart to respond to an ischemic stress is the observation in the current study that
following I/R, aged females have lower levels … Because both PKCδ and PKCε promote cardiac …

… AM, Korzick DH (2007) Estrogen deficiency decreases ischemic tolerance in the aged rat
heart: Roles of PKCdelta, PKCepsilon, Akt, and GSK3beta. Am J Physiol Regul Integr Comp …

… PI3K-Akt-GSK-3β signaling and estrogen – Interestingly, … role for PKCε targeting in the aged,
E 2 -deficient female rat … between age-dependent declines in ischemic tolerance and altered …

… in females increases with age, 1 but it is significantly lower than … of the LV function was less
in ovariectomized rats than in … of Akt/PKB and translocation of PKCε and, in male rat hearts, a …

… women exhibit reduced tolerance to myocardial ischemia … the effects of age-associated
estrogen deficiency on innate … cardiac function relative to heart from aged, intact female rats, …

… AM, Korzick DH (2007) Estrogen deficiency decreases ischemic tolerance in the aged rat
heart: roles of PKCdelta, PKCepsilon, Akt, and GSK3beta. Am J Physiol Regul Integr Comp …

… team involving estrogen-deprived female rats demonstrated … of cardiac autonomic regulation
and mitochondrial function, … TNF production, and reduced PI3K and Akt activation which …

… Estrogen deficiency decreases ischemic tolerance in the aged rat heart: roles of PKCdelta,
PKCepsilon, Akt, and GSK3beta. Am J Physiol Regul Integr Comp Physiol 292: R800–R809, …

… function did not vary substantially between young and aged … On the other hand, levels of
the survival kinases AKT, ERK1/2 and … and bcl-2, bcl-xl, bax and fas in the rat heart and brain …

… mediate mitochondrion function by binding with pI3K-Akt, pGC-… attenuated or lost in
hyperlipidemic rat heart is a new finding in … , significantly reduced the cardiac damage and …