Extracorporeal photopheresis (ECP) is a leukapheresis-based therapy that uses 8-
methoxypsoralen and ultraviolet A irradiation. Used alone or in combination with biological
agents, ECP is an established and effective therapy for advanced cutaneous T-cell
lymphoma. ECP has also shown promising efficacy in a number of other severe and difficult-
to-treat conditions, including systemic sclerosis, graft-versus-host disease, prevention and
treatment of rejection in solid organ transplantation, and Crohn disease. Furthermore, the …