Sarcopenia is characterized by a loss of muscle mass and function that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries. At the intracellular level,
mitochondrial population alterations are considered as key contributors to the complex
etiology of sarcopenia. Mitochondrial dysfunctions lead to reactive oxygen species
production, altered cellular proteostasis, and promotes inflammation. Interestingly, the
receptor for advanced glycation end-products (RAGE) is a pro-inflammatory receptor …