… with HLA specificities of HTLV-I … that HTLV-I carriers and patients with HTLV-I-associated
diseases were ethnically segregated by two categories of HLA haplotypes, ethnospecific HLA …

… HTLV-I specific immune response seen in HAM/TSP patients. The proliferation and HTLV-I
tax expression of HTLV-I infected … HLA, HTLV-I genomic integration site, HTLV-I tax subtype, …

… with asymptomatic HTLV-I carriers. We hypothesized that HLA alleles control HTLV-I provirus
… Here we show that, after infection with HTLV-I, the class I allele HLA-A*02 halves the odds …

… to a single HTLV-I antigen, Tax, plays a decisive part in the outcome of HTLV-I infection. …
Previous indications 33, 34 that HLA-DRB1*0101 was associated with a higher risk of HAM/…

… HTLV-I carriers, we investigated human leukocyte antigen (… , we analyzed HLA DRB1-DQB1
haplotypes of the HTLV-I carriers … the HTLV-I-carrying Andes natives had one of the five HLA …

… (HLA) allele, HLA-A*02 (HLA-A2) have only half the risk of developing HAM/TSP as those
who lack this allele. Because HLA … of CTLs, this observation suggests that HLA-A*02 restricted …

… The frequency of HLACw*08 was also significantly increased in HAM/TSP patients … of
HLADRB1*01 increases the risk of HAM/TSP in HTLV-I-infected individuals and HLACw*08 …

… In this study, we tested the hypothesis that class I HLA heterozygosity is beneficial in
HTLV-I infection. The class I-restricted T cell response exerts selection pressure on the viral …

… HAM/TSP patients and HTLV-I carriers, the interaction … involve in outcome of HTLV-I
infection in infectedindividuals. … CD8+ human leukocyte antigen (HLA) class I and CD4+ HLA …

… Indeed, HLA associations with such neuroimmunological … HLA haplotypes and HTLV-I-specific
immune responsiveness of HAM in comparison with those of ATLT-., to elucidate the HLA …