High amylose starch consumption induces obesity in Drosophila melanogaster and metformin partially prevents accumulation of storage lipids and shortens lifespan …

OB Abrat, JM Storey, KB Storey, VI Lushchak - … and Physiology Part A …, 2018 - Elsevier
There are very few studies that have directly analyzed the effects of dietary intake of slowly
digestible starches on metabolic parameters of animals. The present study examined the
effects of slowly digestible starch with high amylose content (referred also as amylose
starch) either alone, or in combination with metformin on the development, lifespan, and
levels of glucose and storage lipids in the fruit fly Drosophila melanogaster. Consumption of
amylose starch in concentrations 0.25–10% did not affect D. melanogaster development …
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