The innate and adaptive immune systems work as a complex interplay between different cell
types, involving cytokines and chemokines mediating extracellular and paracrine effects. At
the intracellular level, the inflammatory cascade is mediated by multifaceted processes that
have been better described in the last 10 years. Immunosuppressive agents available in
clinical practice act at different points of those cascades at the intracellular or extracellular
level. Those drugs can mediate their effects on one or more cell types finally limiting …