Induction of rapid eye movement sleep by carbachol infusion into the pontine reticular formation in the rat
P Bourgin, P Escourrou, C Gaultier, J Adrien - Neuroreport, 1995 - journals.lww.com
CHOLINERGIC regulation of sleep and wakefulness was studied in freely moving rats
locally infused with various doses of carbachol into the pontine reticular formation. Induction
of REM sleep occurred when carbachol was infused specifically into the posterior oral
pontine reticular nucleus (PnO). This effect was observed with 1–10 ng of carbachol, and
lasted for at least 6 h. It was antagonized by atropine (100–200 ng) infused into the same
site 15 min before carbachol (10 ng), indicating that REM sleep induction resulted from the …
locally infused with various doses of carbachol into the pontine reticular formation. Induction
of REM sleep occurred when carbachol was infused specifically into the posterior oral
pontine reticular nucleus (PnO). This effect was observed with 1–10 ng of carbachol, and
lasted for at least 6 h. It was antagonized by atropine (100–200 ng) infused into the same
site 15 min before carbachol (10 ng), indicating that REM sleep induction resulted from the …
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