The current spectrum of disorders associated to clinical spasms with onset in infancy is
wider than previously thought; accordingly, its terminology has changed. Nowadays, the
term Infantile spasms syndrome (ISs) defines an epileptic syndrome occurring in children
younger than 1 year (rarely older than 2 years), with clinical (epileptic: ie, associated to an
epileptiform EEG) spasms usually occurring in clusters whose most characteristic EEG
finding is hypsarrhythmia [the spasms are often associated with developmental arrest or …