Inhibition of Trypanosoma cruzi by plant extracts used in Chinese medicine

D Lirussi, J Li, JM Prieto, M Gennari, H Buschiazzo… - Fitoterapia, 2004 - Elsevier
In this work, we assessed the effect of extracts obtained from 17 plants used in traditional
Chinese medicine. These extracts were tested in vitro with the epimastigote form of
Trypanosoma cruzi, clone Bra C15 C2, at 27° C in F-29 medium at a concentration of 100
μg/ml in axenic cultures. Allopurinol was used as reference drug. Seven plant extracts
showed inhibitory activities lower than 25%. Pueraria lobata, Mahonia beaei, Dictamus
dasycarpus, Kochia scoparia, Sophora flavescens and Ligustrum lucidum showed effects …
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