… CF is a Th17 disease, we enrolled a cohort of adult patients with cystic fibrosis (mean age
22… aeruginosa and who were undergoing pulmonary exacerbation requiring hospitalization [9]. …

… IL-17 has been found to be elevated in many inflammatory lung diseases, including cystic
fibrosis (CF) and chronic obstructive pulmonary disease (2). Moreover, Concanavalin A …

… . A Th17-/Th2-skewed cytokine profile in cystic fibrosis lungs represents a potential risk
factor for Pseudomonas aeruginosa infection. Am J Respir Crit Care Med 2013;187:621–9. …

… cystic fibrosis (CF), but its cellular sources and role in the pathogenesis of CF lung disease
… -like lung disease, and determined the effects of genetic deletion of Il17a and Rag1 on the …

… CF as a Th17 disease and suggest that peripheral blood Th17 levels may be … cystic fibrosis
transmembrane conductance regulator (CFTR) is not clear, because elevated levels of Th17 …

… Cystic fibrosis (CF) is an autosomal-recessive disorder caused by different mutations in the
CF transmembrane regulator (CFTR) gene, coding for a protein that mainly acts as a chloride …

… (ABPA) (16, 17), a hypersensitivity condition to Aspergillus colonization, affecting about
10… may influence Aspergillus-dependent lung diseases in CF. Considering that tryptophan …

… Cystic fibrosis (CF) is a genetic disease leading to chronic bacterial airway infection and
inflammation. T helper 17 (Th17… IL-23 is an important inducer of IL-17 and IL-22 production. The …

… Interleukin (IL)-17 is pivotal in orchestrating the activity of neutrophils. Neutrophilic
inflammation is the dominant pathology in cystic fibrosis (CF) lung disease. We investigated IL-17 …

… of cystic fibrosis lung infection and inflammation to investigate the role of IL-… of IL-17 in cystic
fibrosis lung disease and the therapeutic validity of attenuating IL-17 activity in cystic fibrosis. …