Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through …
Background Brown macroalgae have attracted attention because they display a wide range
of biological activities, including antitumoral properties. Inthis study we isolated isololiolide
from Cystoseira tamariscifolia for the first time. Purpose To examine the therapeutical
potential of isololiolide against tumor cell lines. Methods/Study design The structure of the
compound was established and confirmed by 1D and 2D NMR as well as HRMS spectral
analysis. The in vitro cytotoxicity was analyzed by colorimetric 3-(4, 5-dimethylthiazol-2-yl)-2 …
of biological activities, including antitumoral properties. Inthis study we isolated isololiolide
from Cystoseira tamariscifolia for the first time. Purpose To examine the therapeutical
potential of isololiolide against tumor cell lines. Methods/Study design The structure of the
compound was established and confirmed by 1D and 2D NMR as well as HRMS spectral
analysis. The in vitro cytotoxicity was analyzed by colorimetric 3-(4, 5-dimethylthiazol-2-yl)-2 …
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