Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours (LEOPARD-2): a multicentre, patient-blinded, randomised controlled …

J Van Hilst, T de Rooij, K Bosscha… - The lancet …, 2019 - thelancet.com
Background Laparoscopic pancreatoduodenectomy may improve postoperative recovery
compared with open pancreatoduodenectomy. However, there are concerns that the
extensive learning curve of this complex procedure could increase the risk of complications.
We aimed to assess whether laparoscopic pancreatoduodenectomy could reduce time to
functional recovery compared with open pancreatoduodenectomy. Methods This
multicentre, patient-blinded, parallel-group, randomised controlled phase 2/3 trial was …

Laparoscopic versus open pancreatoduodenectomy for pancreatic or peri-ampullary tumours

J van Hilst, N de Graaf, S Festen, MA Hilal… - The Lancet …, 2021 - thelancet.com
Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours:
a multicentre, open-label, randomised controlled trial. … This annual volume reduction might
have explained the different outcomes we observed during the LAELAPS-2 training
programme and the LEOPARD-2 trial. … Laparoscopic versus open pancreatoduodenectomy
for pancreatic or periampullary tumours: a multicentre, open-label, randomised controlled trial. …
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