The detrimental effects of fetal exposure to extreme levels of alcohol during pregnancy, such
as the subsequent occurrence of childhood physical, cognitive, and behavioral deficits, are
well known. Some investigators have suggested that there is a dose-response effect, with
light drinking during pregnancy primarily affecting behavioral and adaptive functions and
heavy drinking causing more serious developmental defects and problems. Accordingly,
mild to moderate social drinking during pregnancy could be associated with long-term infant …

Please cite this paper as: Robinson M, Oddy W, McLean N, Jacoby P, Pennell CE, de Klerk
N, Zubrick S, Stanley F, Newnham J. Low–moderate prenatal alcohol exposure and risk to
child behavioural development: a prospective cohort study. BJOG 2010; 117: 1139–1152.
Objective To examine the association of fetal alcohol exposure during pregnancy with child
and adolescent behavioural development. Design The Western Australian Pregnancy
Cohort (Raine) Study recruited 2900 pregnancies (1989–91) and the 14‐year follow up was …