[HTML][HTML] Microfluidic Approaches for Manipulating, Imaging, and Screening C. elegans

BP Gupta, P Rezai - Micromachines, 2016 - mdpi.com
Micromachines, 2016mdpi.com
The nematode C. elegans (worm) is a small invertebrate animal widely used in studies
related to fundamental biological processes, disease modelling, and drug discovery. Due to
their small size and transparent body, these worms are highly suitable for experimental
manipulations. In recent years several microfluidic devices and platforms have been
developed to accelerate worm handling, phenotypic studies and screens. Here we review
major tools and briefly discuss their usage in C. elegans research.
The nematode C. elegans (worm) is a small invertebrate animal widely used in studies related to fundamental biological processes, disease modelling, and drug discovery. Due to their small size and transparent body, these worms are highly suitable for experimental manipulations. In recent years several microfluidic devices and platforms have been developed to accelerate worm handling, phenotypic studies and screens. Here we review major tools and briefly discuss their usage in C. elegans research.
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