[HTML][HTML] Modulating cholesterol homeostasis to build a better T cell

Y Kidani, SJ Bensinger - Cell metabolism, 2016 - cell.com
Y Kidani, SJ Bensinger
Cell metabolism, 2016cell.com
There is great interest in discovering targets for in vitro manipulation of autologous T cells
that enhance their cytotoxicity against tumor targets as a potent cancer immunotherapy. In a
recent Nature paper, Xu and colleagues reveal new insights into the link between cellular
cholesterol metabolism and CD8 T cell functions.
There is great interest in discovering targets for in vitro manipulation of autologous T cells that enhance their cytotoxicity against tumor targets as a potent cancer immunotherapy. In a recent Nature paper, Xu and colleagues reveal new insights into the link between cellular cholesterol metabolism and CD8 T cell functions.
cell.com
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