Non-mouse models of atherosclerosis: approaches to exploring the translational potential of new therapies

D Kamato, I Ilyas, S Xu, PJ Little - International Journal of Molecular …, 2022 - mdpi.com
… and inflammation, and a consideration of suitable animal models, both mouse and non-mouse
models, as addressed in this review, which add to the value of atherosclerosis research. …

Mouse models of atherosclerosis

S Potteaux, H Ait-Oufella, Z Mallat - Drug Discovery Today: Disease Models, 2007 - Elsevier
Mouse models of plaque rupture One of the most important limits of these two mice models
of atherosclerosis comes from the fact that these mice do not present spontaneous plaque …

An accelerated mouse model for atherosclerosis and adipose tissue inflammation

A Neuhofer, B Wernly, L Leitner, A Sarabi… - Cardiovascular …, 2014 - Springer
… In order to develop and standardize a mouse model reflecting … atherosclerosis we investigated
the effect of a common high-fat diet and a sucrose-enriched high-fat diet in LDLR -/- mice. …

Diabetic atherosclerosis mouse models

KK Wu, Y Huan - Atherosclerosis, 2007 - Elsevier
models is a perfect diabetic atherosclerosis mouse model. … atherosclerosis mouse models
to identify the features of each model that closely resemble human diabetic atherosclerosis

Research methods for animal models of atherosclerosis

Y Zhang, M Fatima, S Hou, L Bai… - Molecular medicine …, 2021 - spandidos-publications.com
… PCSK9-AAV mice were a new line of mouse models for atherosclerosis research created
by two groups (57,58). One of the best advantages of these mice is that atherosclerotic lesions …

The role of an experimental model of atherosclerosis: apoE-knockout mice in developing new drugs against atherogenesis

J Jawien - Current pharmaceutical biotechnology, 2012 - ingentaconnect.com
mice has changed the face of atherosclerosis research. Gene-targeted mouse models has
changed the face of atherosclerotic … of the new theory of atherosclerosis: as an inflammatory …

Animal models of atherosclerosis–supportive notes and tricks of the trade

A Gisterå, DFJ Ketelhuth, SG Malin… - Circulation …, 2022 - Am Heart Assoc
atherosclerotic plaques in the 1980s. The new immunologic tools together with genetically …
mouse models laid the foundation for deciphering the inflammatory etiology of atherosclerosis

[HTML][HTML] A practical approach to using mice in atherosclerosis research

SC Whitman - The Clinical Biochemist Reviews, 2004 - ncbi.nlm.nih.gov
mice as an animal model of atherosclerosis, and is directed towards the researcher new to
using mice to perform atherosclerosis … many of the current mouse models that are available, …

Animal models of atherosclerosis

YT Lee, V Laxton, HY Lin, YWF Chan… - Biomedical …, 2017 - spandidos-publications.com
… relationship and relevant atherosclerotic pathology observed in porcine systems (71,72),
drug testing is predictive for efficacy of drugs in humans compared to the mouse model. It can …

Dietary chitosan inhibits hypercholesterolaemia and atherogenesis in the apolipoprotein E-deficient mouse model of atherosclerosis

DJ Ormrod, CC Holmes, TE Miller - Atherosclerosis, 1998 - Elsevier
… of atherosclerotic plaque. We have tested this hypothesis using the apolipoprotein E-…
mouse model of atherosclerosis. This hypercholesterolaemic animal develops atherosclerosis