… , especially genetically modified mouse models 1, have enabled many discoveries of
disease mechanisms 2, but treatment of atherosclerosis still relies on the old discovery that low-…

Background Atherosclerosis is a common and serious vascular disease predisposing
individuals to myocardial infarction and stroke. Intravascular plaques, the pathologic lesions of …

The enzyme 15-lipoxygenase (15-LO) plays a role in atherogenesis (also known as
atherosclerosis), but the underlying mechanisms are unclear. We found that 15(S)-…

… Mouse models of atherosclerosis and the effect of lipoprotein … in building the mouse as a
model of atherosclerosis and to … of mice that are susceptible to early atherosclerosis are often …

… models featuring spontaneous or induced plaque rupture/thrombosis. This review summarizes
current literature on the animal models of vulnerable atherosclerotic … of mouse models …

… of the roles of animal models in the study of atherosclerosis. For … model of atherosclerosis,
and rabbits seem likely to have continued major usefulness in future studies of atherosclerosis…

… useful mouse models to study hyperlipidemia and atherosclerosis. Normally, mice carry …
the very rapid metabolism of remnant clearance in mice, which hamper metabolic studies. In …

… goals of each study, mouse is most frequently used. This chapter will describe experimental
protocols of mouse models of chronic atherosclerosis. Mouse genes are named according to …

… Many mouse models of atherosclerosis recapitulate facets of … that lesions in mouse models
develop to the stage of generating … evaluating results from mouse models of atherosclerosis. …

… Here, we review the genetic data elucidated from mouse models of atherosclerosis, as well
as significant associations for human coronary artery disease. Furthermore, we discuss in …