Zoledronic acid and risedronate in the prevention and treatment of glucocorticoid-induced osteoporosis (HORIZON): a multicentre, double-blind, double-dummy …

DM Reid, JP Devogelaer, K Saag, C Roux, CS Lau… - The Lancet, 2009 - thelancet.com
… to daily oral risedronate for prevention and treatment of glucocorticoid-induced osteoporosis.
… Use of oral corticosteroids in the community and the prevention of secondary osteoporosis: …

Single annual injectable treatment for postmenopausal osteoporosis

RD Chapurlat - Expert Opinion on Drug Delivery, 2008 - Taylor & Francis
… Conclusion: Yearly zoledronic acid presents a new option for the treatment of postmenopausal
osteoporosis, with the perspective of improving the long-term persistence of therapy …

Update on the use of zoledronic acid in the management of osteoporosis

DM Reid - Current osteoporosis reports, 2010 - Springer
osteoporosis market. Although there are no final results from head-to-head antifracture
osteoporosis … ZOL to date is the HORIZON glucocorticoid-induced osteoporosis trial in which 833 …

Osteoporosis: current concepts

I Akkawi, H Zmerly - Joints, 2018 - thieme-connect.com
… Bone turnover biomarker detection may be useful in monitoring osteoporosis treatment and
assessing fracture risk but not for diagnosis of osteoporosis. Management of osteoporosis

New horizons: novel approaches to enhance healthspan through targeting cellular senescence and related aging mechanisms

T Tchkonia, AK Palmer… - The Journal of Clinical …, 2021 - academic.oup.com
… Regarding age-related osteoporosis, senescent cells accumulate in bone with aging both
in mice and humans (32). Elimination of senescent cells from p16 Ink4a -INK-ATTAC mice led …

Effects of antiresorptive therapies on glucose metabolism: results from the FIT, HORIZON‐PFT, and FREEDOM trials

AV Schwartz, AL Schafer, A Grey… - Journal of Bone and …, 2013 - academic.oup.com
… In HORIZON, 7736 postmenopausal women aged 65 to 89 years were stratified into two
groups based on current use of other osteoporosis medications and were randomized within the …

Zoledronic acid in the management of osteoporosis: the HORIZON trials

EM Lewiecki - Clinical Practice, 2008 - search.proquest.com
… , hip and other fractures in women with postmenopausal osteoporosis treated over a period
of 3 years. The HORIZON Recurrent Fracture Trial demonstrated that an annual infusion of …

… acid and change in abdominal aortic calcification over 3 years in postmenopausal women with osteoporosis: results from the HORIZON Pivotal Fracture Trial

G Cai, HI Keen, LV Host, D Aitken, LL Laslett… - Osteoporosis …, 2020 - Springer
… This study was a post hoc analysis of the HORIZON Pivotal Fracture Trial evaluating the …
women with osteoporosis receiving either zoledronic acid or placebo from the HORIZON Pivotal …

New national osteoporosis guidance—implications for geriatricians

CL Gregson, JE Compston - Age and ageing, 2022 - academic.oup.com
… -line anti-osteoporosis therapy; the new concept of ‘very high fracture risk’ which should
prompt consideration of use of parenteral anti-osteoporosis therapy; new guidance regarding …

Current options for the management of postmenopausal osteoporosis

MP Lecart, JY Reginster - Expert opinion on pharmacotherapy, 2011 - Taylor & Francis
… for the management of primary osteoporosis in women. Expert opinion: The availability of
new therapeutic agents makes clinical decision making in osteoporosis more complex. …