… in the development and application of nonviral vectors in gene therapy. However, many
problems remain to be resolved before nonviral gene therapy can become a standard clinical …

… nonviral delivery systems that can be used for gene therapy … major nonviral vectors that are
currently used in gene therapy … and in vivo barriers in gene transfer. Recent advancement in …

… performed a phase I dose escalation study of IL-2 non-viral gene therapy with advanced head
and neck … Exciting progress is being made in the use of systemic non-viral gene therapy. …

… non-viral gene therapy for a variety of disorders, including cystic fibrosis, cancer, and peripheral
vascular disease. Non-viral techniques may soon allow gene therapy … gene therapy for …

… a long-lasting gene expression system is also an important theme for nonviral gene therapy.
To date… of enhancement in the efficiency, specificity and temporal control of nonviral vectors. …

… .who.int/trialsearch} using the MESH terms non-viral vectors, gene transfer vehicle, vectors
in gene therapy, gene therapy, non-viral gene transfer. No restrictions were applied on the …

… and manufacturability of gene carrier formulations. We present an overview of gene-based
therapies focusing on non-viral gene delivery systems and the genetic therapeutic tools that …

… therapy for lymphoma, a cancer of the white blood cells, is being planned. Lipoplexes and
naked DNA are not the only nonviral approaches to gene therapy. … for nonviral gene therapy …

… Non-viral vectors, although less efficient at introducing and maintaining foreign gene …
Polycation–DNA complexes are particularly attractive for non-viral gene therapy. To perform…

… therapeutic gene product. This review will provide insights into the potentials of plasmid-…
gene therapy and critical evaluation of gene delivery sciences and clinical applications of gene …