Optimized platelet‐rich fibrin with the low‐speed concept: growth factor release, biocompatibility, and cellular response
M Fujioka‐Kobayashi, RJ Miron… - Journal of …, 2017 - Wiley Online Library
Background: Over the past decade, use of leukocyte platelet‐rich fibrin (L‐PRF) has gained
tremendous momentum in regenerative dentistry as a low‐cost fibrin matrix used for tissue
regeneration. This study characterizes how centrifugation speed (G‐force) along with
centrifugation time influence growth factor release from fibrin clots, as well as the cellular
activity of gingival fibroblasts exposed to each PRF matrix. Methods: Standard L‐PRF served
as a control (2,700 revolutions per minute [rpm]‐12 minutes). Two test groups using low …
tremendous momentum in regenerative dentistry as a low‐cost fibrin matrix used for tissue
regeneration. This study characterizes how centrifugation speed (G‐force) along with
centrifugation time influence growth factor release from fibrin clots, as well as the cellular
activity of gingival fibroblasts exposed to each PRF matrix. Methods: Standard L‐PRF served
as a control (2,700 revolutions per minute [rpm]‐12 minutes). Two test groups using low …
RE: Optimized platelet-rich fibrin with the low-speed concept: Growth factor release, biocompatibility, and cellular response.
N Pinto, M Quirynen - Journal of Periodontology, 2018 - europepmc.org
… Impact of g force and timing on the characteristics of platelet-rich fibrin matrices. … Do
the fibrin architecture and leukocyte content influence the growth factor release of platelet
concentrates? An evidence-based answer comparing a pure platelet-rich plasma (P-PRP)
gel and a leukocyte- and platelet-rich fibrin (L-PRF). …
the fibrin architecture and leukocyte content influence the growth factor release of platelet
concentrates? An evidence-based answer comparing a pure platelet-rich plasma (P-PRP)
gel and a leukocyte- and platelet-rich fibrin (L-PRF). …
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