Treating severe malaria in pregnancy: a review of the evidence

SD Kovacs, MJ Rijken, A Stergachis - Drug Safety, 2015 - Springer
… , stillbirth, or congenital anomalies associated with first … quinine or artesunate for the
treatment of severe malaria in first … drug exposure after receiving oral artesunate than the same …

Intravenous Artesunate for Transfusion-Transmitted Plasmodium vivax Malaria in a Preterm Neonate

GP Prashanth, MB Maralihalli, PS Bagalkot… - Pediatrics, 2012 - publications.aap.org
… However, there are no specific guidelines available for the treatment of severe malaria
among neonates. We preferred parenteral artesunate over chloroquine and oral artesunate

… -dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria …

AK Tshefu, O Gaye, K Kayentao, R Thompson… - The Lancet, 2010 - thelancet.com
… P falciparum malaria with either artemether-lumefantrine or mefloquine and artesunate as …
in patients with P vivax malaria of pyronaridine-artesunate compared with chloroquine. This is …

Pharmacokinetics of dihydroartemisinin following oral artesunate treatment of pregnant women with acute uncomplicated falciparum malaria

R McGready, K Stepniewska, SA Ward, T Cho… - European journal of …, 2006 - Springer
… The mean (SD) [90% range] body weight of women in the study was 50.6 (5.8) [41–60] kg,
resulting in a mean daily dose of 200 mg oral artesunate per woman, for 3 days. Overall …

A randomized comparison of artesunate-atovaquone-proguanil versus quinine in treatment for uncomplicated falciparum malaria during pregnancy

R McGready, EA Ashley, E Moo, T Cho… - The Journal of …, 2005 - academic.oup.com
malaria for a randomized, open-label trial with a restricted sequential trial design of 7 days
of supervised quinine (SQ7) versus 3 days of artesunate-… , or congenital abnormality rates in …

Artesunate/dihydroartemisinin pharmacokinetics in acute falciparum malaria in pregnancy: absorption, bioavailability, disposition and disease effects

R McGready, AP Phyo, MJ Rijken… - British journal of …, 2012 - Wiley Online Library
… CONCLUSIONS This study demonstrates the effects of malaria on oral ARS drug disposition
are greater than those of pregnancy. This probably results from a disease related reduction …

A randomised controlled trial of artemether-lumefantrine versus artesunate for uncomplicated Plasmodium falciparum treatment in pregnancy

R McGready, SO Tan, EA Ashley… - PLoS …, 2008 - journals.plos.org
… falciparum malaria, but efficacy was inferior to 7 d artesunate … of artesunate which responded
to oral chlorpheniramine and … The newborn anthropometric results and neurological scores …

Artemisinin derivatives in the treatment of falciparum malaria in pregnancy

R McGready, T Cho, JJ Cho, JA Simpson… - Transactions of the …, 1998 - academic.oup.com
… There was no congenital abnormality in any of the newborn children, and the 46 children …
treated with oral artesunate in this study. The advantage of oral artesunate over intravenous …

Antimalarial treatment in infants

LC Kalkman, T Hanscheid, S Krishna… - Expert opinion on …, 2022 - Taylor & Francis
… While data on neonatal and congenital malaria is limited, our … treatment for severe malaria
when artesunate is unavailable [… artesunate in infants, the opposite seems true for oral

Randomized comparison of quinine-clindamycin versus artesunate in the treatment of falciparum malaria in pregnancy

R McGready, T Cho, L Villegas, A Brockman… - Transactions of the …, 2001 - Elsevier
… There were 3 neonatal deaths, 2 QC7 and 1 A7, all of whom died in the first week of life
from causes unrelated to … Oral clindamycin in the treatment of acute uncomplicated falciparum …