Polygenic risk scores in prostate cancer risk assessment and screening
L Byrne, AE Toland - Urologic Clinics, 2021 - urologic.theclinics.com
Prostate cancer (PCa) is the most common cancer among men with a lifetime risk of 12%
and median age of diagnosis of 66. 1 In 2020, 191,930 new cases are expected to be
diagnosed in the United States. 1 Established risk factors for PCa include genetic factors,
African ancestry, older age, and family history of PCa (discussed in Yasin Bhanji and
colleagues' article,“Prostate Cancer Predisposition,” elsewhere in this issue). 2 African
American (AA) men are 1.8 times more likely to be diagnosed with PCa than men of …
and median age of diagnosis of 66. 1 In 2020, 191,930 new cases are expected to be
diagnosed in the United States. 1 Established risk factors for PCa include genetic factors,
African ancestry, older age, and family history of PCa (discussed in Yasin Bhanji and
colleagues' article,“Prostate Cancer Predisposition,” elsewhere in this issue). 2 African
American (AA) men are 1.8 times more likely to be diagnosed with PCa than men of …
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