Recent studies have shown that the antifungal itraconazole (ITZ), when in associations with
benznidazole (BNZ), is a potential treatment for Chagas disease. Therefore, the objective of
the present study was to evaluate the compatibility of ITZ with BNZ and with selected
pharmaceutical excipients. Differential scanning calorimetry (DSC), derivative
thermogravimetry (DTG), Fourier transform infrared spectroscopy (FTIR), optical microscopy
and kinetic analyses under isothermal conditions were performed. The results showed …