Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke
C Bouleti, T Mathivet, B Coqueran… - European heart …, 2013 - academic.oup.com
Aims Given the impact of vascular injuries and oedema on brain damage caused during
stroke, vascular protection represents a major medical need. We hypothesized that
angiopoietin-like 4 (ANGPTL4), a regulator of endothelial barrier integrity, might exert a
protective effect during ischaemic stroke. Methods and results Using a murine transient
ischaemic stroke model, treatment with recombinant ANGPTL4 led to significantly decreased
infarct size and improved behaviour. Quantitative characteristics of the vascular network …
stroke, vascular protection represents a major medical need. We hypothesized that
angiopoietin-like 4 (ANGPTL4), a regulator of endothelial barrier integrity, might exert a
protective effect during ischaemic stroke. Methods and results Using a murine transient
ischaemic stroke model, treatment with recombinant ANGPTL4 led to significantly decreased
infarct size and improved behaviour. Quantitative characteristics of the vascular network …
[PDF][PDF] Protective effects of angiopoietin-like 4 on cerebrovascular and functional damages in ischaemic stroke
Aims Given the impact of vascular injuries and oedema on brain damage caused during
stroke, vascular protection represents a major medical need. We hypothesized that
angiopoietin-like 4 (ANGPTL4), a regulator of endothelial barrier integrity, might exert a
protective effect during ischaemic stroke.
stroke, vascular protection represents a major medical need. We hypothesized that
angiopoietin-like 4 (ANGPTL4), a regulator of endothelial barrier integrity, might exert a
protective effect during ischaemic stroke.
以上显示的是最相近的搜索结果。 查看全部搜索结果